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Fengchao Jiang Selected Research

5- (3- (4- (4- benzylpiperazin- 1- yl)- N- (4- phenylthiazol- 2- yl))propanamide

8/2020TJ-M2010-5, a novel MyD88 inhibitor, corrects R848-induced lupus-like immune disorders of B cells in vitro.
10/2019Implication of myeloid differentiation factor 88 inhibitor TJ-M2010-5 for therapeutic intervention of hepatocellular carcinoma.
2/2019Short-term use of MyD88 inhibitor TJ-M2010-5 prevents d-galactosamine/lipopolysaccharide-induced acute liver injury in mice.
1/2019Modulating the conformation of the TIR domain by a neoteric MyD88 inhibitor leads to the separation of GVHD from GVT.
1/2019A novel MyD88 inhibitor attenuates allograft rejection after heterotopic tracheal transplantation in mice.

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Fengchao Jiang Research Topics

Disease

3Neoplasms (Cancer)
10/2019 - 01/2005
2Inflammation (Inflammations)
08/2020 - 02/2019
1Experimental Arthritis
01/2021
1Rheumatoid Arthritis
01/2021
1Arthritis (Polyarthritis)
01/2021
1Immune System Diseases (Immune Disorders)
08/2020
1Hepatocellular Carcinoma (Hepatoma)
10/2019
1Neoplasm Metastasis (Metastasis)
10/2019
1Necrosis
10/2019
1Body Weight (Weight, Body)
02/2019
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2019
1Bronchiolitis
01/2019
1Airway Obstruction (Choking)
01/2019
1Amyloidosis
10/2018
1Alzheimer Disease (Alzheimer's Disease)
10/2018
1Vitamin K Deficiency
10/2018
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2016
1Opioid-Related Disorders (Opiate Addiction)
09/2006
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2005

Drug/Important Bio-Agent (IBA)

55- (3- (4- (4- benzylpiperazin- 1- yl)- N- (4- phenylthiazol- 2- yl))propanamideIBA
08/2020 - 01/2019
2Myeloid Differentiation Factor 88IBA
10/2019 - 01/2016
1Interleukin-6 (Interleukin 6)IBA
01/2021
1CytokinesIBA
01/2021
1C-Reactive ProteinIBA
01/2021
1AutoantibodiesIBA
08/2020
1Amyloid (Amyloid Fibrils)IBA
10/2018
1Proteins (Proteins, Gene)FDA Link
10/2018
1Vitamin KFDA Link
10/2018
1Vitamin K 3 (Menadione)FDA Link
10/2018
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
09/2006
1CurcuminIBA
01/2005
1ProdrugsIBA
01/2005
1EsterasesIBA
01/2005

Therapy/Procedure

1Therapeutics
10/2019
1Intraperitoneal Injections
02/2019
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2019
1Lung Transplantation
01/2019
1Aftercare (After-Treatment)
01/2005
1Drug Therapy (Chemotherapy)
01/2005